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Which analgesic is an NMDA antagonist helpful in preventing wind-up?

Question 1

This neurokinin1 receptor antagonist is labeled for the prevention and treatment of acute vomiting in dogs and for the treatment of vomiting in cats but may also have visceral analgesic properties resulting in MAC reduction of sevoflurane during stimulation of the ovarian ligament in cats and dogs:

Question 2

This controversial analgesic has a variable weak M1, mu agonist effect in dogs:

Question 3

This analgesic can be used as a constant rate infusion for soft tissue, orthopedic, neurological and intra-ocular procedures but may have many other useful benefits including antiarrythimc properties, free radical scavenger, anti-inflammatory and antimicrobial activity:

Question 4

This class of analgesics works by inhibition of the cyclo-oxygenate (COX) enzymes and should not be administered with steroids:

Question 5